A genetic predisposition for colorectal cancer in inflammatory bowel disease.
نویسندگان
چکیده
منابع مشابه
Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation.
Patients with ulcerative colitis and Crohn's disease are at increased risk for developing colorectal cancer. To date, no known genetic basis has been identified to explain colorectal cancer predisposition in these inflammatory bowel diseases. Instead, it is assumed that chronic inflammation is what causes cancer. This is supported by the fact that colon cancer risk increases with longer duratio...
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Patients with inflammatory bowel disease (IBD) are at an increased risk of developing colorectal cancer (CRC), and key contributing factors include chronic colonic inflammation and the extent and duration of disease. This increase in risk is more likely to result from chronic inflammation of the colonic mucosa than from any clearly defined genetic predisposition. However, globally, the true mag...
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Crohn’s disease (CD) and ulcerative colitis (UC), the two clinical entities comprising idiopathic inflammatory bowel disease (IBD), are complex disorders with a proven genetic predisposition. Several systematic genome wide searches for susceptibility genes in patients with IBD have reported linkage to specific regions of the genome. In particular, many replication studies, including a large int...
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Crohn’s disease (CD) and ulcerative colitis (UC), the two clinical entities comprising idiopathic inflammatory bowel disease (IBD), are complex disorders with a proven genetic predisposition. Several systematic genome wide searches for susceptibility genes in patients with IBD have reported linkage to specific regions of the genome. In particular, many replication studies, including a large int...
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عنوان ژورنال:
- Gut
دوره 29 11 شماره
صفحات -
تاریخ انتشار 1988